Endocrine Abstracts

The aim of the current study was to determine whether the porcine ovary was capable of metabolizing polybrominated diphenyl ether – BDE-47, which is the most abundant congener found in wildlife and in humans. It have been showed by us that this congener disrupt ovarian function by direct action on steroidogenesis. In the current study we analyzed the activity and expression of enzymes involved in phase I (CYP1A1 and CYP2B1/2) and phase II (SULT1A and COMT) of BDE-47 metab...